We designed this dose to assist and stimulate your master hormone gland, the pineal gland that makes Melatonin at night and Serotonin during the day. When these two hormones get out of balance, we feel depressed during the day and cannot sleep well at night. A guaranteed formula for stress. Let our Cheerful dose put things back in the norm. Best taken in the morning when you wake and/or at night before sleep, Cheerful will re-level your hormones and help you feel happy again!